骨膜蛋白(POSTN)重組蛋白
Recombinant Periostin (POSTN)
OSF-2; PDLPOSTN; PN; Osteoblast Specific Factor 2
- 編號URPH339Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌
- 預(yù)測分子量18.1kDa
- 實際分子量18kDa(差異分析請參閱說明書)
- 片段與標簽Asn24~Asn173 with N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 90%
- 等電點7.7
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 432 ¥ 1080 ¥ 2160 ¥ 6480 ¥ 16200
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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SDS-PAGE圖
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通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPH339Ra01 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPH339Ra02 | 骨膜蛋白(POSTN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAH339Ra01 | 骨膜蛋白(POSTN)多克隆抗體 | WB; IHC |
| UPAH339Ra02 | 骨膜蛋白(POSTN)多克隆抗體 | WB |
| UFAH339Ra01 | 抗骨膜蛋白(POSTN)多克隆抗體 | FCM |
| ULAH339Ra71 | 骨膜蛋白(POSTN)多克隆抗體(生物素標記) | WB |
| USEH339Ra | 骨膜蛋白(POSTN)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMH339Ra | 骨膜蛋白(POSTN)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Blood | Circulating Periostin Is Elevated In Patients With Hemoglobinopathies and Correlates With Bone Mineral Density In Double Heterozygous Sickle-Cell/Beta-Thalassemia Patients; A Novel Marker Of Bone Strength? [Bloodjournal: Source] |
| The Journal of Clinical Endocrinology & Metabolism | Serum periostin is associated with fracture risk in postmenopausal women: a 7 years prospective analysis of the OFELY study [Pubmed: 24628551] |
| J Clin Endocrinol Metab. | Serum Periostin Is Associated With Fracture Risk in Postmenopausal Women: A 7-Year Prospective Analysis of the OFELY Study [Pubmed:24628551] |
| Rheumatology (Oxford). | Circulating periostin levels in patients with AS: association with clinical and radiographic variables, inflammatory markers and molecules involved in bone formation [Pubmed:25349442] |
| Journal of Periodontal Research | Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease [Pubmed:25529858] |
| 新醫(yī)學(xué) | 血清內(nèi)脂素水平與多囊卵巢綜合征的相關(guān)性研究 [Xinyixue:Source] |
| Osteoarthritis | Serum periostin is associated with prevalent knee osteoarthritis and disease incidence/progression in women: the OFELY study [PubMed: 26072384] |
| Endocrine | Serum periostin is a potential biomarker for non-alcoholic fatty liver disease: a case– control study [PubMed: 26362060] |
| Blood?Cancer?Journal | High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly … [pubmed:27716740] |
| Metabolism.? | Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity. [pubmed:28521873] |
| Osteoporosis International | Circulating periostin levels increase in association with bone density loss and healing progression during the early phase of hip fracture in Chinese older women [pubmed:28382553] |
| Molecular Diagnosis & Therapy | The Utility of Biomarkers in Osteoporosis Management [pubmed:28271451] |
| Journal of Bone and Mineral Research | Cortical and trabecular bone microstructure did not recover at weight-bearing skeletal sites and progressively deteriorated at non-weight-bearing sites during the year following International Space Station missions [doi:10.1002] |
| Clinical Cases in Mineral and Bone Metabolism | Periostin and sclerostin levels in juvenile Paget's disease [pubmed:29263750] |
| Calcified?Tissue?International | Development of a New Immunoassay for Human Cathepsin K-Generated Periostin Fragments as a Serum Biomarker for Cortical Bone [pubmed:28725907] |
| Wiley | Characterization of a sandwich ELISA for the quantification of all human periostin isoforms [pubmed:28493527] |
| International Osteoporosis Foundation and National Osteoporosis Foundation | Interaction between LRP5 and periostin gene polymorphisms on serum periostin levels and cortical bone microstructure [pubmed:29038835] |
| Bone | Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones [pubmed:28323143] |
| Clinica Chimica Acta | Association between serum periostin concentrations and outcome after acute spontaneous intracerebral hemorrhage [pubmed:28882488] |
| Clinica Chimica Acta | Serum periostin concentrations and outcomes after severe traumatic brain injury [pubmed:28668564] |
| Tumor Biology | Predictive and prognostic value of serum periostin in advanced non–small cell lung cancer patients receiving chemotherapy [pubmed:28459197] |
| Journal of Bone and Mineral Research | Serum Levels of a Cathepsin-K Generated Periostin Fragment Predict Incident Low-Trauma Fractures in Postmenopausal Women Independently of BMD and FRAX [pubmed:28766739] |
| ОСОБЕННОСТИ СОСТОЯНИЯ ЗДОРОВЬЯ НОВОРОЖДЕННЫХ, РОЖДЕННЫХ ОТ МАТЕРЕЙ С БРОНХИАЛЬНОЙ АСТМОЙ [2017; 62:(4)] | |
| Endocrine | Circulating periostin in patients with nonalcoholic fatty liver disease. [pubmed:27738886] |
| Molecular Medicine Reports | Periostin cross?reacts with the renin?angiotensin system during liver fibrosis development [pubmed:28849131] |
| The Journal of Biological Chemistry | Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice [Pubmed:29929978] |
| Calcified?Tissue?International | The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis [Pubmed:29916127] |
| Journal of Endocrinological Investigation | Increased serum periostin concentrations are associated with the presence of diabetic retinopathy in patients with type 2 diabetes mellitus [Pubmed:29349642] |
| Wiener klinische Wochenschrift | Rheumatoid arthritis in remission [] |
| Clinical?and Experimental Medicine | Myostatin and other musculoskeletal markers in lung transplant recipients [Pubmed: 30317402] |
| Experimental?and?Clinical?Endocrinology?&?Diabetes | Polycystic Ovary Syndrome is Associated with Elevated Periostin Levels [Pubmed: 30372763] |
| ИСПОЛЬЗОВАНИЕ СЫВОРОТОЧНОГО ПЕРИОСТИНА В КАЧЕСТВЕ МАРКЕРА ОБОСТРЕНИЙ АСТМЫ У ДЕТЕЙ [] | |
| Bone | Tartrate-resistant acid phosphatase 5b, but not periostin, is useful for assessing Paget's disease of bone [Pubmed: 31051316] |
| Journal of Clinical Laboratory Analysis | Identification and diagnostic value of pleural fluid periostin and serum periostin of malignant pleural effusions in patients with non–small‐cell lung cancer [Pubmed: 31268191] |
| Bone | Serum periostin is associated with cancer mortality but not cancer risk in older home-dwelling men: A 8-year prospective analysis of the STRAMBO study [Pubmed: 31812700] |
| FASEB J | Fibronectin rescues aberrant phenotype of endothelial cells lacking either CCM1, CCM2 or CCM3 [Pubmed: 32515053] |
| Journal of Reproductive Immunology | Serum and placental periostin levels in women with early pregnancy loss [Pubmed: 32460058] |
| Annals of Medical Research | Evaluation of periostin levels in gingival crevicular fluid and peri-implant sulcus fluid in patients with periodontal and peri-implanter disease: A cross-sectional?… [] |
| Myostatin and Markers of Bone Metabolism in Dermatomyositis [] | |
| Am J Physiol Heart Circ Physiol | Periostin promotes arterial calcification through PPAR|?-related glucose metabolism reprogramming [33834866] |
| International Journal of Chronic Obstructive Pulmonary Disease | High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease [33814903] |
| J Bone Oncol | Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma [34150488] |
| Rambam Maimonides Med J | The Relationship between Serum Periostin Levels and Neutrophil¨CLymphocyte Ratio with Lesion Localization and Acute Prognosis in Acute Ischemic Stroke [34137680] |
| Rambam Maimonides Medical Journal | First Admission Neutrophil–Lymphocyte Ratio May Indicate Acute Prognosis of Ischemic Stroke [34137680] |
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