神經(jīng)調節(jié)素1(NRG1)真核蛋白
Eukaryotic Neuregulin 1 (NRG1)
ARIA; GGF; HGL; HRG; HRGA; NDF; SMDF; Acetylcholine receptor-inducing activity; Glial growth factor; Heregulin; Neu differentiation factor; Sensory and motor neuron-derived factor
- 編號UEPB866Hu61
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源真核表達
- 宿主293F Cell
- 內毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜, 細胞核, 分泌
- 預測分子量26.41kDa
- 實際分子量45kDa(差異分析請參閱說明書)
- 片段與標簽Ser20~Lys246 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點8.7
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應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 暫無報價 暫無報價 暫無報價 暫無報價 暫無報價
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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SDS-PAGE圖
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通過ISO 9001、ISO 13485質量體系認證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質期內，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務
相關產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| UAPB866Hu01 | 神經(jīng)調節(jié)素1(NRG1)活性蛋白 | Cell?culture;?Activity?Assays. |
| URPB866Hu01 | 神經(jīng)調節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPB866Hu62 | 神經(jīng)調節(jié)素1(NRG1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPB866Hu61 | 神經(jīng)調節(jié)素1(NRG1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB866Hu01 | 神經(jīng)調節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
| ULAB866Hu71 | 神經(jīng)調節(jié)素1(NRG1)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| UMAB866Hu25 | 神經(jīng)調節(jié)素1(NRG1)單克隆抗體 | WB |
| UMAB866Hu27 | 神經(jīng)調節(jié)素1(NRG1)單克隆抗體 | ICC/IF |
| UMAB866Hu22 | 神經(jīng)調節(jié)素1(NRG1)單克隆抗體 | WB |
| UMAB866Hu21 | 神經(jīng)調節(jié)素1(NRG1)單克隆抗體 | WB |
| UMAB866Hu23 | 神經(jīng)調節(jié)素1(NRG1)單克隆抗體 | WB; IHC |
| UMAB866Hu24 | 神經(jīng)調節(jié)素1(NRG1)單克隆抗體 | IHC |
| USEB866Hu | 神經(jīng)調節(jié)素1(NRG1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMB866Hu | 神經(jīng)調節(jié)素1(NRG1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UKSB866Hu01 | 神經(jīng)調節(jié)素1(NRG1)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It(ELISA Kit) Yourself" |
參考文獻
| 雜志 | 參考文獻 |
| Neuroscience Letter | Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom [Cyagen: source] |
| PLoS One. | ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis [PubMed: PMC3519469] |
| The Journal of Clinical Investigation | Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration [PubMed: PMC3428100] |
| Physiol Behav | Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress [PubMed: 26626816] |
| J Toxicol Sci.? | Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. [Pubmed:26961615] |
| journal of cellular and molecular medicine | Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. [pubmed:28271613] |
| Transl Psychiatry. | Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. [pubmed:28267150] |
| Human?Molecular?Genetics | A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas [Pubmed: 30335132] |
| Aging (Albany NY) | Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin [Pubmed: 32920546] |
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