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突觸核蛋白α(SNCa)多克隆抗體

Polyclonal Antibody to Synuclein Alpha (SNCa)

SNC-A; aSYN; PD1; PARK1; PARK4; NACP; Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein; Non-A4 component of amyloid precursor

  • 突觸核蛋白α(SNCa)多克隆抗體 產(chǎn)品包裝(模擬)
  • 突觸核蛋白α(SNCa)多克隆抗體 產(chǎn)品包裝(模擬)
  • 突觸核蛋白α(SNCa)多克隆抗體 DAB staining on IHC-P; Sample: Mouse Cerebrum Tissue; Primary Ab: 10ug/ml Rabbit Anti-Human SNCa Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • 突觸核蛋白α(SNCa)多克隆抗體 DAB staining on IHC-P;
    Sample: Mouse Testis Tissue;
    Primary Ab: 10ug/ml Rabbit Anti-Human SNCa Antibody
    Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • PAB222Hu01.jpg WB圖
  • 突觸核蛋白α(SNCa)多克隆抗體 Western Blot; Samples: Lane1: Rat Cerebrum lysate; Lane2: Rat Cerebellum lysate; Lane3: Mouse Cerebrum lysate; Lane4: Mouse Cerebellum lysate;
    Primary Ab: 0.05μg/ml Rabbit Anti-Human SNCa Antibody
    Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Certificate 通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對(duì)SNCa的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別SNCa。

用法

Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲(chǔ)存

經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

贈(zèng)品

相關(guān)產(chǎn)品

編號(hào) 適用物種：Homo sapiens (Human，人) 應(yīng)用(僅供研究使用，不用于臨床診斷！)
URPB222Hu01 突觸核蛋白α(SNCa)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
UPAB222Hu01 突觸核蛋白α(SNCa)多克隆抗體 WB,IHC
ULAB222Hu71 突觸核蛋白α(SNCa)多克隆抗體(生物素標(biāo)記) WB; IHC; ICC.
UMAB222Hu22 突觸核蛋白α(SNCa)單克隆抗體 WB; IHC; ICC; IP.
USEB222Hu 突觸核蛋白α(SNCa)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) Enzyme-linked immunosorbent assay for Antigen Detection.
UAEB222Hu 抗突觸核蛋白α抗體(Anti-SNCa)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) Enzyme-linked immunosorbent assay for Antibody Detection.
ULMB222Hu 突觸核蛋白α(SNCa)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志 參考文獻(xiàn)
The Journal of Clinical Investigation Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration [PubMed: PMC3428100]
Neurobiology of Disease Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission [PubMed: PMC3107939]
Nature Communications Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus [PubMed: PMC3265381]
Provisional chapter Mutations of PARK Genes and Alpha-Synuclein and Parkin Concentrations in Parkinson’s Disease [Intechopen:Source]
Nerodegeneration Apolipoprotein Eε4: A Biomarker for Executive Dysfunction among Parkinson's Disease Patients with Mild Cognitive Impairment [pubmed:29326545]
Experimental gerontology The anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling. [pubmed:29107062]
Neurobiology of Disease Development and biochemical characterization of a mouse model of Parkinson's disease bearing defective glucocerebrosidase activity [Pubmed: 30521842]
molecular and cellular biochemistry Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model [Pubmed: 31820278]
International Journal of Pharmacology Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease [Pubmed: 32084576]
EBioMedicine Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys [Pubmed: 32810825]
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